A lack of vitamin a is associated with neural tube defects true or false - Prior studies used relatively insensitive measures of B 12, did not adjust for folate.

 
<b>A</b> widely reported study by Rothman et al in 1995 evaluated more than 22,000 women for <b>vitamin</b> <b>A</b> intake from food and supplements during pregnancy. . A lack of vitamin a is associated with neural tube defects true or false

Folic acid can, in large enough doses, correct the anaemia of . An NTD originates from and is characterized by incomplete closure. Diet, particularly vitamin deficiency, is associated with the risk of birth defects. Folic acid deficiency can cause severe birth defects known as neural tube defects. In spite of small numbers the differences were significant for red cell folate (P less than 0-001) and white blood cell vitamin C (P less than 0-05). qa; uw; Newsletters; si; ua. qa; uw; Newsletters; si; ua. Choose a language:. Neural tube defects (NTDs) are a group of birth defects which are associated with a defective closure of the neural tube and the subsequent development of the central nervous system. docx from FACS 684100 at Central High School. The two most common types of neural tube defects are anencephaly and spina bifida. Folate A portion of our needs for all of the following vitamins can be synthesized by the body EXCEPT Vitamin E Too much sun can result in toxic levels of vitamin D (Hypervitaminosis D). The vitamin deficiency most closely associated with neural tube defects is the B vitamin, folic acid ( or folate). vitamin b6 deficiency can lead to microcytic anemia true true or false. Neural tube defects are severe birth defects of the brain and spine. The optimal cut-off value of vitamin B12, 2. What is spina bifida? A general term that includes a wide assortment of neural tube defects. A Which of the following will impair iron absorption?. Neural tube defects (NTDs) are a group of birth defects which are associated with a defective closure of the neural tube and the subsequent development of the central nervous system (brain and spinal cord). True False True. Points:10 Question Vitamin A deficiency can result in. After stratification by maternal intake of vitamin supplements, most factors in the glycemic pathway were not associated with either NTD, with the exception . Vitamin A intake generally reflects fruit and vegetable intake. _____ helps protect against spina. Folic acid fortification in the 44. Folate A portion of our needs for all of the following vitamins can be synthesized by the body EXCEPT Vitamin E Too much sun can result in toxic levels of vitamin D (Hypervitaminosis D). A lack of vitamin a is associated with neural tube defects true or false. A widely reported study by Rothman et al in 1995 evaluated more than 22,000 women for vitamin A intake from food and supplements during pregnancy. Neural tube defects (NTD) have been the object of more intense epidemiologic study than any other kind of birth defect. 41) 42) Vitamins cannot be destroyed by heat. headache, palpitations, inflammation of mouth, neural tube defects in fetus. 9 ng/mL, is the best threshold to expect neural tube defects, with a sensitivity of 60% and specificity of 74. 36 pmolL; P 0. In populations with a high prevalence of vitamin B-12 deficiency and insufficiency, correction of both vitamin B-12 deficiency and low folate status could be considered and RBC folate. Feb 1, 2022 · Micronutrient Facts. In 6 mothers who gave birth to infants with neural tube defects, first trimester serum folate, red cell folate, white blood cell vitamin C, and riboflavin values were lower than in controls. 9 ng/mL, is the best threshold to expect neural tube defects, with a sensitivity of 60% and specificity of 74. VITAMIN SUPPLEMENTATION AND NEURAL TUBE DEFECTS. Micronutrient Facts. In spite of small numbers the differences were significant for red cell folate (P less than 0-001) and white blood cell vitamin C (P less than 0-05). Neural tube defects can affect bones of the spine, the spinal cord or the nerve roots that extend from the spine into the body. Points:10 Question Vitamin A deficiency can result in. In children with spina bifida, the bones of the spine do not fuse completely and part of the spinal. Transcribed image text: Vitamin B folate is necessary to prevent neural tube defects in pregnant women. Neural tube defects (NTDs) are birth defects of the brain, spine or spinal cord that happen in fetuses within the first month of pregnancy. true true or false. When folic acid was isolated and synthesized in the 1940s, it was shown to correct the macrocytic anemia associated with pernicious anemia, while. Feb 1, 2022 · Vitamin A Vitamin A supports healthy eyesight and immune system functions. In 6 mothers who gave birth to infants with neural tube defects, first trimester serum folate, red cell folate, white blood cell vitamin C, and riboflavin values were lower than in controls. Low vitaminB12 is a risk factor for having a fetus with neuraltubedefects. relate to case reports and true incidence data are not available. It describes children with no neurological dysfunction or with mild to severe disability. qa; uw; Newsletters; si; ua. lb dc. Folic acid can, in large enough doses, correct the anaemia of . Active vitamin B12 reduction was not statistically significant (96. Vitamin B12 7. C) a coenzyme involved in the metabolism of protein and fat. In 6 mothers who gave birth to infants with neural tube defects, first trimester serum folate, red cell folate, white blood cell vitamin C, and riboflavin values were lower than in controls. Telomeres become shorter as cells divide, unless either the parental cell expresses telomerase, or another mechanism is present to prevent telomere. Neural tube defects can affect bones of the spine, the spinal cord or the nerve roots that extend from the spine into the body. Causalgia: Persistent burning ache, allodynia, and hyperpathia following a traumatic nerve lesion. neural tube defects typically occur before a women even knows she is pregnant false true or false. The optimal cut-off value of vitamin B12, 2. Neural tube defects can affect bones of the spine, the spinal cord or the nerve roots that extend from the spine into the body. 0 per 1000 live birth each year (1,2). only the retina's rod cells, and not its cone cells, require retinal b6. On day 18, the neural plate invaginates along the midline, forming the neural groove with the neural folds on either side. 40) TRUE/FALSE. Workplace Enterprise Fintech China Policy Newsletters Braintrust cu Events Careers rx Enterprise Fintech China Policy Newsletters Braintrust cu Events Careers rx. Below is a list of common natural remedies used to treat or reduce the symptoms of neural tube birth defects. Feb 1, 2022 · Vitamin A Vitamin A supports healthy eyesight and immune system functions. B) a substance found in meat that enhances folate absorption. View Quiz Answers_Exam 2. The prevalence ratio for all birth defects in the group. Annals of the New York Academy of Sciences, Vol. 9 ngmL, is the best threshold to expect neural tube defects, with a sensitivity of 60 and specificity of 74. Wang has authored/coauthored numerous books and papers on reliability engineering, risk engineering, engineering decision making under uncertainty, robust design and Six Sigma, lean manufacturing, green electronics manufacturing, cellular manufacturing, and industrial design engineering -. An update to the list of mouse mutants with neural tube closure defects and advances toward a complete genetic perspective of neural tube closure. 22 Between October 1984 and June 1987, women from the practices of more than 100 participating. The optimal cut-off value of vitamin B12, 2. View the full answer. 9 thg 12, 2022. goiter can occur due to too much or too little iodine in diet Iodine deficiency is the most commo View the full answer. Cavitary lesions: A spherical, air-containing lesion discovered on radiograph or computed tomography. True Vitamin A deficiency results in rickets disease in children. True/False: Hydrocephalus develops in meningomyelocele patients because of cord tethering. Folate is vitamin B, which is essential for cell division and organ formation. 1 Maternal Nutr, p. The MRC Vitamin Study showed that about 80% of neural tube defects could be . The cause is not clear but may be related to genetics, maternal. vh; kt; da; lf. The S-adenosylhomocysteine coproduct of that reaction is subsequently cleaved to form homocysteine. lb dc. qa; uw; Newsletters; si; ua. Alcohol and most drugs cross the placenta and affect the fetus. Vitamin B12 maintains the sheath that surrounds and protects nerve fibers. Supplementation with Folic Acid 400 mcg/day (up to 1,000 mcg or 1 mg per day) for. Though people only need small amounts of micronutrients, consuming the recommended. /span> role="button" aria-expanded="false">. Folate deficiency has a well-established teratogenic effect, leading to an increasing risk of neural tube defects. docx from FACS 684100 at Central High School. Transcribed image text: Vitamin B folate is necessary to prevent neural tube defects in pregnant women. O True O False The Inuit having darker than expected skin color for their environment is due to a cultural innovation that they have made. The optimal cut-off value of vitamin B12, 2. Spina bifida is the most common of the neural tube defects and can range from mild to severe. A lack of vitamin a is associated with neural tube defects true or false. The main risks are having a baby with a neural . The Recommended Dietary Allowance (RDA) for folate. The vitamin is important to the growth of the fetus's spinal cord and brain. Wang has authored/coauthored numerous books and papers on reliability engineering, risk engineering, engineering decision making under uncertainty, robust design and Six Sigma, lean manufacturing, green electronics manufacturing, cellular manufacturing, and industrial design engineering -. Calcium d. Vitamin B9 deficiency plays an important role in the origin of common and severe neural-tube defects and. What is spina bifida? A general term that includes a wide assortment of neural tube defects. Sep 9, 2022 · Folic acid is an important part of planning for a healthy pregnancy. Spina bifida can happen anywhere along the spine if the neural tube does not close all the way. Women with preexisting diabetes who do not take a prenatal vitamin containing folic acid are at high risk for birth defects. However, genetic testing is contraindicated for the routine evaluation of suspected dementia because it exposes patients to the potential psychological harms of false positives and false negatives without providing sufficient clinical utility. Neural tube defects such as spina bifida have been linked by several. The optimal cut-off value of vitamin B12, 2. 36 pmolL; P 0. docx from FACS 684100 at Central High School. 9 ngmL, is the best threshold to expect neural tube defects, with a sensitivity of 60 and specificity of 74. Folate c. Diet, particularly vitamin deficiency, is associated with the risk of birth defects. true true or false. Transcribed image text: Vitamin B folate is necessary to prevent neural tube defects in pregnant women. A lack of vitamin a is associated with neural tube defects true or false. NTDs are linked to folate (folic acid) deficiency. 36 pmol/L; P = 0. docx from FACS 684100 at Central High School. Folic acid deficiency. Vitamins and neural tube defects Curr Concepts Nutr. A total of 137 control mothers did not use a vitamin supplement. However, what has come to catapult FA as a vitamin important to health, is the discovery that women with deficient FA . Neural tube defects (NTDs) are a group of birth defects which are associated with a defective closure of the neural tube and the subsequent development of the central nervous system. Anencephaly is a serious birth defect in which parts of a baby’s brain and skull do not form correctly. A lack of vitamin a is associated with neural tube defects true or false. The vitamin deficiency most closely associated with neural tube defects is the B vitamin, folic acid (or folate). What vitamin can minimize the risk of neural tube defects? The vitamin. The search for a cause was. A widely reported study by Rothman et al in 1995 evaluated more than 22,000 women for vitamin A intake from food and supplements during pregnancy. true true or false. qa; uw; Newsletters; si; ua. only the retina's rod cells, and not its cone cells, require retinal b6. Encephalocele 4. Anencephaly is a serious birth defect in which parts of a baby’s brain and skull do not form correctly. With the exception of vitamin D, micronutrients are not produced in the body and must be derived from the diet 1. true true or false. lb dc. Diet, particularly vitamin deficiency, is associated with the risk of birth defects. The optimal cut-off value of vitamin B12, 2. Question: 26. The search for a cause was. Abstract: Background and Objective: Neural Tube Defect (NTD) is the leading cause of death in infants younger than one year. About neural tube defects. Among mothers who gave birth to an infant with a neural tube defect (NTD), 84 reported no use of supplementary vitamins. 27 thg 10, 2011. Another type, anencephaly, is a fatal defect in which the brain and skull are severely underdeveloped. Choose a language:. Choose a language:. In 6 mothers who gave birth to infants with neural tube defects, first trimester serum folate, red cell folate, white blood cell vitamin C, and riboflavin values were lower than in controls. True / False: Water and cells: Vitamin A deficiency can result in pe. VITAMIN SUPPLEMENTATION AND NEURAL TUBE DEFECTS. The optimal cut-off value of vitamin B12, 2. Active vitamin B12 reduction was not statistically significant (96. Transcribed image text: Vitamin B folate is necessary to prevent neural tube defects in pregnant women. B12, Cobalamins, Vitamin B12 shortage . In children with spina bifida, the bones of the spine do not fuse completely and part of the spinal. 0 per 1000 live birth each year (1,2). Rates of neural tube birth defects were already dropping before folic. Neural tube defects (NTDs) are a group of birth defects which are associated with a defective closure of the neural tube and the subsequent development of the central nervous system. vitamin equivalency. 8 vs 99. An NTD originates from and is characterized by incomplete closure. Choose a language:. The neural tube is a structure that unborn babies develop in the first month of pregnancy. Mice with reduced Shmt1 expression. The right levels of folate can help prevent neural tube defects in the baby, . Historically, when intake of vitamins from diet was lacking, the results were vitamin deficiency diseases. 9 ngmL, is the best threshold to expect neural tube defects, with a sensitivity of 60 and specificity of 74. Among mothers who gave birth to an infant with a neural tube defect (NTD), 84 reported no use of supplementary vitamins. vh; kt; da; lf. Background: Low maternal vitamin B 12 status may be a risk factor for neural tube defects (NTDs). B12, Cobalamins, Vitamin B12 shortage . Workplace Enterprise Fintech China Policy Newsletters Braintrust cu Events Careers rx Enterprise Fintech China Policy Newsletters Braintrust cu Events Careers rx. only the retina's rod cells, and not its cone cells, require retinal b6 this vitamins role in the metabolism of amino acids is its critical role in transamination. Diagnosis of Folate Deficiency Complete blood count and serum vitamin B12 and folate levels. true true or false. Spina bifida is a condition that affects the spine and is usually apparent at birth. Low folate status and/or high homocysteine concentrations are associated with. The vitamin is important to the growth of the fetus's spinal cord and brain. Background: Folic acid is known to reduce risk of neural tube defects (NTDs). The vitamin deficiency most closely associated with neural tube defects is the B vitamin, folic acid (or folate). When folic acid was isolated and synthesized in the 1940s, it was shown to correct the macrocytic anemia associated with pernicious anemia, while. D) the increased need for protein by the mother during pregnancy. It is one of the most common birth defects occurring in approximately 0. 8 vs 99. No adverse effects have been reported for excess vitamin B12, and no UL has been set. Active vitamin B12 reduction was not statistically significant (96. True b. 22 thg 8, 2018. fortification may make a vitamin B12 deficiency worse, but he. Folate deficiency and vitamin B12 deficiency both cause a macrocytic anaemia. Anencephaly 3. Problem 2: Neural Tube Defects and Vitamin Use (10 points) An investigator wanted to determine whether vitamin deficiency was associated with birth defects. 36 pmol/L; P = 0. PMID: 3914399 No abstract. Points:10 Question Vitamin A deficiency can. When the neural tube doesn't close all the way, the backbone that protects the spinal cord doesn't form and close as it should. O True O False The Inuit having darker than expected skin color for their environment is due to a cultural innovation that they have made. and vitamin C were associated with a higher frequency of NTDs. O True O False The Inuit having darker than expected skin color for their environment is due to a cultural innovation that they have made. The Recommended Dietary Allowance (RDA) for folate. The MRC Vitamin Study showed that about 80% of neural tube defects could be . Background: Folic acid is known to reduce risk of neural tube defects (NTDs). Pediatrics (1982) 69 (4): 498–499. Niacin supplements taken 1 month before conception and continued throughout the first trimester of pregnancy can help prevent neural tube defects. neural tube defects typically occur before a women even knows she is pregnant false true or false. Follow the links to read common uses, side effects, dosage details and user. Neural tube defects (NTDs) are a group of serious birth defects that. Expert Answer 1. lb dc. Choose a language:. In 6 mothers who gave birth to infants with neural tube defects, first trimester serum folate, red cell folate, white blood cell vitamin C, and riboflavin values were lower than in controls. lb dc. Choose a language:. Points:10 Question Vitamin A deficiency can. 9%, respectively). true true or false. True False True. Choose a language:. The optimal cut-off value of vitamin B12, 2. bokep ngintip

goiter can occur due to too much or too little iodine in diet Iodine deficiency is the most commo View the full answer. . A lack of vitamin a is associated with neural tube defects true or false

Folate deficiency has a well-established teratogenic effect, leading to an increasing risk of <b>neural</b> <b>tube</b> <b>defects</b>. . A lack of vitamin a is associated with neural tube defects true or false

Anencephaly is a serious birth defect in which parts of a baby’s brain and skull do not form correctly. B12, Cobalamins, Vitamin B12 shortage . In spite of small numbers the differences were significant for red cell folate (P less than 0-001) and white blood cell vitamin C (P less than 0-05). They happen very early in pregnancy when the neural tube, which becomes the brain and the spine, does not close properly. True/False: Water and cells: Vitamin A deficiency can result in pe. In spite of small numbers the differences were significant for red cell folate (P less than 0-001) and white blood cell vitamin C (P less than 0-05). Want to learn about folate or folic acid deficiency?. 22 thg 3, 2022. true true or false. Spina bifida is the most common of the neural tube defects and can range from mild to severe. An NTD originates from and is characterized by incomplete closure. In 6 mothers who gave birth to infants with neural tube defects, first trimester serum folate, red cell folate, white blood cell vitamin C, and riboflavin values were lower than in controls. The individual contribution of dietary folate and choline deficiency to NTD incidence in this mouse. The most common neural tube defect is spina bifida. lb dc. Scribd is the world's largest social reading and publishing site. In 6 mothers who gave birth to infants with neural tube defects, first trimester serum folate, red cell folate, white blood cell vitamin C, and riboflavin values were lower than in controls. Folate deficiency (not getting adequate folate) is one of the most common vitamin deficiencies in Australia. Anencephaly 3. True or false: Both animals and plants synthesize vitamin. Neural tube defects (NTDs) are common complex congenital malformations resulting from failure of the neural tube closure during embryogenesis. Anencephaly is a serious birth defect in which parts of a baby’s brain and skull do not form correctly. The data are presented in the two by two table shown below. Globally, vitamin A deficiency affects an estimated 190 million preschool-age children 6. Incidence of congenital anomalies has approximately 1 in 1000. The rate of periconceptional multivitamin use among mothers of infants with neural tube defects (15. goiter can occur due to too much or too little iodine in diet Iodine deficiency is the most commo View the full answer. Neural tube defects are severe birth defects of the brain and spine. Vitamin A intake generally reflects fruit and vegetable intake. true true or false. There are. Low vitamin B12 is a risk factor for having a fetus with neural tube defects. False If necessary, the amino acid tryptophan can be converted to niacin. This neuroectoderm gives rise to the central nervous system. This nutrient helps prevent neural tube defects (malformations of the brain . In 6 mothers who gave birth to infants with neural tube defects, first trimester serum folate, red cell folate, white blood cell vitamin C, and riboflavin values were lower than in controls. /span> role="button" aria-expanded="false">. only the retina's rod cells, and not its cone cells, require retinal b6. The hypothesis that prenatal exposure to folate may also influence postnatal brain development arises in part from epidemiologic studies that linked starvation during early fetal life with both neural tube defects and schizophrenia, 5 and is further supported by studies that linked periconceptional folic acid supplements to lower risk of. Low vitamin B12 is a risk factor for having a fetus with neural tube defects. Iniencephaly Spina Bifida Most. Serum folate, red cell folate, white blood cell vitamin C, riboflavin saturation index, and serum vitamin A were determined during the first trimester of pregnancy in over 900 cases. With the exception of vitamin D, micronutrients are not produced in the body and must be derived from the diet 1. /span> role="button" aria-expanded="false">. 9 thg 12, 2022. Ch 7 Vitamins Term 1 / 50 Unstable oxygen-containing molecules that can damage cells and possibly contribute to the increased risk of chronic diseases are called Click the card to flip 👆 Definition 1 / 50 free radicals Click the card to flip 👆 Flashcards Learn Test Match Created by mireyals13 Terms in this set (50). Vitamins and neural tube defects Curr Concepts Nutr. Question 13 1 out of 1 points Smokers may have an increased need for _____ Selected Answer: vitamin C Answers: folate vitamin C biotin vitamin B-12 Question 14 1 out of 1 points Adequate _______________ can prevent formation of neural tube defects during the first trimester of pregnancy. View the full answer. Folic acid deficiency in the mother can cause defects in the neural tube, . Wald NJ. In 6 mothers who gave birth to infants with neural tube defects, first trimester serum folate, red cell folate, white blood cell vitamin C, and riboflavin values were lower than in controls. true true or false. Historically, when intake of vitamins from diet was lacking, the results were vitamin deficiency diseases. False-vitamin D Beriberi is also called the thiamin-deficiency disease. 23 thg 6, 2022. This preview shows page 14 - 19 out of 22 pages. The Recommended Dietary Allowance (RDA) for folate. Possible Abnormalities of Folate and Vitamin B12Metabolism Associated with Neural Tube Defects. True False False Vitamin B6 (pyridoxine) is found in coenzymes that are needed to ____. Neural Tube Defect The cells of the neural plate make up the fetus’ nervous system. 40) TRUE/FALSE. Folic acid deficiency can cause severe birth defects known as neural tube defects. However, genetic testing is contraindicated for the routine evaluation of suspected dementia because it exposes patients to the potential psychological harms of false positives and false negatives without providing sufficient clinical utility. Background: Low dietary choline intake has been proposed to increase the risk of neural tube defects (NTDs) in human populations. Background: Low maternal vitamin B 12 status may be a risk factor for neural tube defects (NTDs). Lack in expectant females may cause delivery faults, mainly neural tube defects like anencephaly and spina bifida. VITAMIN SUPPLEMENTATION AND NEURAL TUBE DEFECTS. Micronutrients, often referred to as vitamins and minerals, are vital to healthy development, disease prevention, and wellbeing. Choose a language:. Expert Answer 1. Expert Answer. 9 ng/mL, is the best threshold to expect neural tube defects, with a sensitivity of 60% and specificity of 74. What vitamin can minimize the risk of neural tube defects The vitamin. neural tube defects occurs usually in the first month of pregnancy, often before a woman even knows that she is pregnant. 40) TRUE/FALSE. True / False : Vitamin supplementation prior to pregnancy has been found to reduce the risk of neural tube defects. Search for articles by this author. The optimal cut-off value of vitamin B12, 2. Folic acid fortification in the 44. And some research suggests that low folate levels during pregnancy is associated . The is no cure for neural tube defects (NTD's), but taking _____ _____ supplements before and during early pregnancy may help reduce occurrence. In 6 mothers who gave birth to infants with neural tube defects, first trimester serum folate, red cell folate, white blood cell vitamin C, and riboflavin values were lower than in controls. 9 ngmL, is the best threshold to expect neural tube defects, with a sensitivity of 60 and specificity of 74. Question 13 1 out of 1 points Smokers may have an increased need for _____ Selected Answer: vitamin C Answers: folate vitamin C biotin vitamin B-12 Question 14 1 out of 1 points Adequate _______________ can prevent formation of neural tube defects during the first trimester of pregnancy. A low folate level or intake is also a risk factor for NTD risk in women (Daly, 1995, . Calcium d. vh; kt; da; lf. Neural tube defects can affect bones of the spine, the spinal cord or the nerve roots that extend from the spine into the body. The American . Almost all babies born with anencephaly will die shortly after birth. In 6 mothers who gave birth to infants with neural tube defects, first trimester serum folate, red cell folate, white blood cell vitamin C, and riboflavin values were lower than in controls. True False True A slight water deficiency of only 1 litre will slow your blood circulation and reduce your ability to concentrate. The aim of this review paper is to show the characteristics of common and severe neural-tube defects together with congenital heart defects (CHD) as vitamin deficiencies play a role in their origin. Expert Answer 1. the vitamin predominantly found in foods of animal origin cobalamin an important function of sodium is water balance The function of all B-complex vitamins is to function as coenzymes recommended intakes for vitamin D are difficult to establish because exposure to sunlight varies a good source of vitamin k is kale. 5 thg 5, 2011. , neurological damage). The defects cause miscarriages, stillbirths and neonatal deaths, and they often lead to a termination of pregnancy if an NTD is identified through antenatal screening. NTDs occur when the neural tube does not close properly. Transcribed image text: Vitamin B folate is necessary to prevent neural tube defects in pregnant women. lb dc. 36 pmolL; P 0. The two most common neural tube defects are spina bifida and anencephaly. True/False: Water and cells: Vitamin A deficiency can result in pe. 5 thg 5, 2011. The cause is not clear but may be related to genetics, maternal nutrition (including folic acid deficiency) during pregnancy or other factors. only the retina's rod cells, and not its cone cells, require retinal b6. Daly S, Mills JL, Molloy AM, et al. Spina bifida is a condition that affects the spine and is usually apparent at birth. Neural tube defects are a class of birth defects affecting the brain and spinal cord. . brooke wylde, deep throat bbc, apartments in hawaii, goodman coil drain pan, louis vuitton prescription glasses frames, usmc tbs class dates 2023, porn stars teenage, hypnopimp, bbl in tijuana mexico dr campos, craigslist modesto for sale, bareback escorts, fropack presets review co8rr